Holobiosys (INCI: Propanediol (and) Water (Aqua) (and) Gentiana Lutea Root Extract (and) Sphingomonas Ferment Extract) is a COSMOS-certified and microbiota-friendly active ingredient. It includes wild yellow gentian root extract enhanced by fermentation with a rare bacteria from aerobiota. It restructures skin, boosts hyaluronic acid synthesis and restores skin hydration with smoothing effects on wrinkles while invigorating the skin holobiont.